Would you like to get more
information about biological potential of your chemical compounds?
- It is possible with
computer program PASS (Prediction of Activity Spectra for
Substances), which predicts the
biological activity spectrum for a compound on the basis of its structural formula.
PASS Inet predicts 3678 pharmacological
effects, mechanisms of action, mutagenicity, carcinogenicity,
teratogenicity and embryotoxicity. The result of prediction is displayed in your
computer automatically via Internet for free.
To obtain the prediction for your compound you have to register.
- Why PASS might be useful for you?
- PASS gives you hits in the
following:
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Finding
most probable new leads with required activity spectra among the compounds from in-house
and commercial data bases.
|
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Revealing
new effects and mechanisms of action for the old substances in corporate and private data
bases. |
|
Providing
the basis for selection of the most prospective compounds for high throughput screening
from the set of available samples. |
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Determining the assays
that are more relevant for a particular compound. |
General description of the method is presented here (see the left menu panel)
You can download and use locally PASS demo version, which predicts 50
biological activities, and test it on your computer: PASSDEMO.ZIP
To take active part in PASS project you may
join to
PASS Users Association
In case of any question or suggestion, please, do not
hesitate to contact us: pass@ibmc.msk.ru
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